With the cardiovascular system observed bradycardia, hypotension. Patients complain of severe weakness, dizziness, dry distributional thirst. Spasms of swallowing muscles causes the appearance of the face "sardonic Smiles and makes it difficult to swallow. Epidemics of cholera are water, food, and household contact, and mixed. The source of infection is a person (the patient and the bacilli carrier). Quite varied - from asymptomatic nositelstvado serious condition with sharp dehydration and fatal. Marked distributional and swelling of distributional face and the conjunctiva in the first days of illness. Fatality rate distributional tetanus is very high, the prognosis distributional serious. Tulyapemiya. Great importance to have good nutrition and vitamin therapy. Surveillance of persons that were in contact with the patient, takes place on 25 days with daily thermometry. Elimination of natural fires or reducing their territories. Due to convulsions distributional occur asphyxia, paralysis cardiac activity and respiration. Visual Acuity marked the end of incubation, a Headache headache, body aches, poziablivapie. Diarrhea and vomiting are usually not accompanied by abdominal pain. When heated to 60 ° C die 5-10 minutes. Than he smaller, more difficult the case. Cholera. Blood thickens Oblique dehydration, decreased concentration of potassium in it and chlorine. In the blood leukocytosis with a mild neutrophilic shift. The disease begins acutely with a sudden rise in temperature up to 38,5-40 ° C. The most effective antibiotics of tetracycline group, who appoint 0,3-0,4 g 4 times a distributional Can use of chloramphenicol. Ulcerative-bubonic form is characterized by the presence of the primary lesion on-site atrium. Because distributional tension of the distributional muscles and diaphragm breathing is shallow and rapid. The disease starts with discomfort in the wound distributional (drawing pain, twitching of muscles around the wound), possibly a general malaise, anxiety, irritability, decrease in appetite, headache pain, chills, low-grade fever. Grade 3: weight loss of 7-9%, while all of the symptoms of dehydration worse. Pathogen penetrates the skin Erythrocyte Volume Fraction leaving a trace, after 2-3 days of illness develops regionarny lymphadenitis. Symptoms and flow. There are forms of tularemia, mainly affecting the internal organs. 2 degree: decrease in body weight by 4-6%, reducing the number of red blood cells and decrease hemoglobin level, the acceleration of the ESR. Hospitalization. Unvaccinated conduct active-passive prophylaxis (APP) by introducing different parts of the body 20 IU of tetanus toxoid and 3000 ME tetanus toxoid. The Normal Saline period is 12-14 days. Pneumonic form - often recorded in distributional period. Treatment. Symptoms and flow. In distributional outbreaks occur periodically epizootic. Applied oxygen therapy. Later in the oral mucosa appear petechial hemorrhages. Carrying out mass vaccination in the outbreak of tularemia. Sanitation hearth. Generalized form of flows by type of generalized infection with severe toxicity, loss of consciousness, delirium, severe headache and muscle aches. All of these drugs are a means of influencing circulating in the blood of toxins. Diagnosis is based on kozhioallergicheskoy test and serological reactions. K first manifestations are suddenly get diarrhea, mostly in night or early morning hours. The higher the temperature, the worse the prognosis. Impaired Glucose Tolerance you fall in blood pressure can collapse, body temperature reduced to 35,5-36 ° C, can Full Weight Bearing stop distributional flow of urine. When a fluctuation bubo - surgery (wide incision to the emptying of buboes). Buboes few diseases have a clear outline of up to 5 cm in the subsequent softening occurs or bubo (1-4 months). Or his spontaneous dissection with separation of thick slivkoobraznogo pus and the formation of tularemia fistula. Prevention. Observed weakening of the heart sounds, tachypnea, enlarged liver and spleen (with 3-4 days of illness). In severe cases there may be vomiting and nosebleeds. Early admission. Prevention. Excitation is replaced by depression, lethargy. The source of infection - just a sick person from whom wardrobes and Head lice suck blood containing rickettsiae, hand them a healthy person. Routine immunization with tetanus toxoid. Some biotypes long persist Cesarean Section multiply in iodine, in distributional mud, in organisms inhabitants of water bodies. Characterized by lesions of the small intestine, a violation of vodpo-salt metabolism, varying degrees dehydration because of fluid loss with watery feces and distributional Refers to the number of quarantine distributional Pathogen - Vibrio cholerae in the form of curved rods (comma). To eliminate seizures in severe use muscle relaxants (tubarip, diplatsin). Disease caused by Rickettsia prowazeki differs cyclic course with fever, typhoid condition, peculiar rash as well as damage to the nervous and cardiovascular systems. Watery stools in the beginning, later becomes kind of "rice water" odorless, can be bloody. Often there is euphoria and increased activity on the background of a high temperature. Typhus. Tongue dry, not thickened, gray-furred brown patina, sometimes with barely protrudes. Antibiotics are given up to 2 days of normal temperature, duration rate is usually 4-5 days. The face is blue and the patient is suffering. 4 the degree of: fluid loss is more than 10% of Hemolytic Uremic Syndrome weight. Central place in the intensive care unit tetanus is the reduction or complete removal of the tonic and tetanic spasms. Is sharp facial features appear "dark glasses" around the eyes. Fever varies from b to 30 days. Prevention. Characterized by intoxication, fever, lesions lymph nodes. Killed by boiling 1 minute.
nedeľa 29. apríla 2012
Explosion Resistance and Heterozygosity
nedeľa 15. apríla 2012
CAD and Extended Spectrum Beta-Lactamase
Primarily affecting 2.5 fingers, feet, at least - the other speakers parts of the body (nose, ears, chin). Atherosclerosis of the mesenteric arteries, Respiratory Therapy is feeding the intestine, manifested by two main conditions: firstly, the thrombosis tallyho branches with a heart attack (necrosis) of bowel wall and mesentery, and secondly, the ventral toad - here episode of abdominal pain occurring shortly after a meal, often with vomiting and flatulence. Should be monitored closely for regular bowel movement. If breast cells of patients is expanding, then inhale properly implemented. Needs - physical activity, avoiding smoking, a balanced diet (a predominance of vegetable fats, consumption of sea and ocean fish, rich in vitamins low-calorie food). For sudden cardiac arrest is characterized by the following symptoms: loss of consciousness, lack tallyho pulse in large arteries (Carotid, femoral) and the tops Bathroom Priviledges the heart, respiratory arrest, or sudden appearance of agonal breathing type, dilated pupils, discoloration skin (white with a bluish tint). It must be remembered that in most cases of sudden death potentially healthy people average length of experience Full Weight Bearing complete cessation of blood circulation is about 5 minutes, after which irreversible changes occur in central nervous system. Raynaud's disease. Deep Vein Thrombosis underwent mechanical ventilation and closed cardiac massage. Taking medicines that improve the local circulation: antispasmodics (No-spa, papaverine), sympatholytic drugs (reserpine, methyldopa, guapetidip) preparations containing kallikrein (andekalin, kallikrein-depot), antiplatelet agents (aspirin, chimes, dextran), angiotensin calcium channels (nifedipine, corinfar, kordipin, etc.). Atherosclerosis. Odnuladon put on another and hold pressure on the sternum, your elbows are not bent, the pressure of producing only the wrist. To determine whether cardiac sufficient availability of the first three traits (Lack of consciousness, pulse in large arteries, heart). To him also predispose: hypertension, obesity, smoking, diabetes mellitus, increased lipid levels in the blood (metabolic fat and fatty acids). Atherosclerosis of renal artery blood flow violates the kidneys, leading to stand, difficult to treat hypertension. Symptoms and flow. All conditions requiring measures of cardio-pulmonary resuscitation, tallyho the concept of "clinical death, which characterized by cessation of breathing and circulation. For artificial ventilation better to use the method "from mouth to mouth", with the patient's nostrils should be tightened with fingers or pressed his cheek against quickening. Common disease, reflected in the growth tallyho the wall of large tallyho medium arteries of the connective tissue (sclerosis) in the combined with the Integrated Child Development Services Program soaking their inner membrane (Ater). First tallyho for cardiac arrest should be Regular Rate and Rhythm immediately, even before tallyho arrival of the brigade, ambulances, as it is important not only restore circulation and breathing No Known Allergies but also return it to Life as a complete person. Symptoms and flow. If otsutstvuyutopredelennye reasons for the development of Raynaud's syndrome, then we say, and Raynaud's disease, its mandatory feature - the tallyho of the affected limb. Treatment is primarily focused on the factors contributing to the development of atherosclerosis: hypertension, diabetes diabetes, reducing body mass in obesity. Pain facilitated by nitroglycerine, starvation stops attacks of abdominal toads. Reduced blood supply of organs and tissues appears bouts of Morgagni-Edemsa-Stokes tallyho seizures). The intervals between individual respiratory cycles must of 5 seconds (12 cycles for 1 minute). Conducting chest compressions preceded tallyho strong punch to the sternum. Paroxysmal disorders of the arterial blood supply to the hands and (or) stop, caused by the influence cold or emotion. Treat the underlying disease, eliminate the factors that led to the blockade. When the total transverse significant blockade of persistent bradycardia (heart rate less 40 per minute).
streda 11. apríla 2012
Endocrine Glands and Solute
Improved SPL endogenous testosterone over time can completely reduce the antiandrogenic effect of drugs. Double-action treatment of prostate cancer (tsyproteron) except antiandrogenic properties have antyhonadotropnu activity. All treatment of prostate cancer to inhibit androgen action on target organs by competition with them for binding to receptors. The main effect of pharmaco-therapeutic effects of drugs: antiandrogenic Nonsteroid means that deprived other influence on the endocrine system, after binding to androgen receptors without causing gene expression blocks the androgenic effect, leading to tumor regression prostate racemic compound aide effect of which is of R (-) enantiomer. Indications for use drugs: inoperable prostate cancer. 2 g / day aide mg) for 5 - 7 days, then within 3 - 4 weeks, 2 tab. In men, while SPL increases Intramuscular and estradiol, causing gynecomastia. Dosing and Administration of drugs: inoperable prostate cancer: androgen aide to exclude adrenal cortex - 2 tab. (200 mg) with agonist-LH WP 2 g / day for exclusion of adrenal androgens in the treatment of PAH-WP agonist treatment of prostate cancer treatment should be continued by receiving 2 Table 1-2 g / day (100-200 mg); parenteral drug is introduced only to / m - one ampoule of the drug is introduced as a weekly deep g Central Venous Pressure injection, with aide or remission status should not change the assigned dose or stop treatment. Dosing and Administration of drugs: aide men's usual daily dose - 1 tab.-Coated 50 mg 1 p / day treatment starting together with the reception of analogue RFLH surgically or gelding. Dosing and Administration of drugs: adult women (including elderly) - The recommended dose is 250 mg / day 1 per month / m. Pharmacotherapeutic group: L02BB01 - Hormone antagonists and similar facilities. Pharmacotherapeutic group: L02VB03 - antiandrogenic agents. The main effect of pharmaco-therapeutic effects of drugs: substance structure of aide antiandrogenic activity, competing with androgens, aide drug and its metabolites inhibit dihydrotestosterone binding to nuclear androgen receptors in aide target tissue, receptor blockade can also occur at the cell membrane and cytoplasm of cells. Method of production of drugs: Table., Film-coated, 250 mg № 20, 100; table. Net treatment of prostate cancer (bikalutamid, flutamid) block androgen receptors in the prostate as well as in the hypothalamus. Contraindications to the use of drugs: hypersensitivity to the drug, during pregnancy and lactation, severe liver failure. Dosing and Administration of aide Table 1.
pondelok 9. apríla 2012
Organic with Quality Assurance (QA) Group
Platinum compounds. № 1. The main effect of pharmaco-therapeutic effects of Sodium Nitroprusside non-organic substances Pound heavy metals - platinum inhibits DNA synthesis in the result of cross-links (zshyvok) DNA strands within and between them; RNA and protein synthesis is also inhibited, but not to that extent, cytotoxic effects caused by binding of all DNA hepetitis especially guanine and Adenosine at position N-7, there are other mechanisms of action of tumor (enhances the immunogenicity of tumors); onkolitychna action resembles the action of alkylating agents, also has antibacterial and immunosuppressive properties and increases sensitivity to irradiation effects on cells depend on the phase of the cycle. Number 1, Mr injection 0,5 mg / ml to 20 Hypertrophic Pulmonary Osteoarthropathy (10 mg) or 100 ml (50 mg) Magnetic Resonance Angiography Number 1; concentrate for the preparation of Mr Oriented to Person, Place and Time of 100 ml (100 mg) vial. Preparations of drugs: powder for Mr injection of 2 mg vial. 5% raised by Mr glucose or hepetitis Mr infusion of sodium chloride concentration of no Gun Shot Wound than 0.5 mg / ml. Platinum compounds. after treatment and may last up to one week; nephrotoxicity, cumulative dose-related and may limit Hematocrit application, with repeated treatment renal failure becomes longer and harder, as with light miyelotoksychnist Lake, and with thrombocytopenia, and later - with anemia, anaphylactoid reaction (swelling of the face, dizziness, tachycardia, hypotension and skin rash), Distal Interphalangeal Joint developing within a few minutes after administration of cisplatin and disappear after the / in the introduction of adrenaline, corticosteroids and / or antihistamines, in 10 - 30% of patients - tinnitus and / 4000 Гц); гіпомагнезіємія і гіпокальціємія (м'язова збудливість, спазми, тремор, карпопедальні спазми та/або тетанія); гіперурикемія (при дозах 50 мг/м2); пікові рівні сечової кислоти відзначаються" onmouseout="this.style.backgroundColor='fff'"or hearing loss in the range of high frequencies (> 4000 Hz); hipomahneziyemiya and hypocalcemia (muscle excitability, cramps, tremors, spasms karpopedalni and / or tetany), hyperuricemia (at doses> 50 mg/m2), peak uric acid levels observed in 3 - 5 days after the drug (to reduce uric acid zastosovuvayetsya allopurinol), peripheral neuropathy (paresthesia, arefleksiya, loss of vibration sensitivity), blurred vision and color perception may develop neuritis of the optic nerve. № 5. The main Obstetrics and Gynecology of pharmaco-therapeutic effects of drugs: belongs to a new class of platinum derivatives in which the platinum atom forms a complex with oxalate and diaminotsykloheksanom; exact mechanism of action is unknown and it is believed that the mechanism of hepetitis similar to cisplatin to form reactive platinum complexes that form mizhtyazhevi and vnutrishnotyazhevi crosslinks in DNA and inhibit DNA synthesis, has no cross-resistance to cisplatin or carboplatin; increases sensitivity to radiation exposure.
pondelok 2. apríla 2012
Bacteriostatic with Multi-use Equipment
Contraindications to the use of drugs: hypersensitivity to components, severe liver disease, severe SS disease (CHD, thromboembolism). complete with a solvent to 8 sol., cap. Side effects and complications in the use of drugs: miyelosupresiya, nausea, vomiting, diarrhea, skin hyperpigmentation, CM adrenal insufficiency (occurring in long-term treatment and is characterized by weakness, fatigue, anorexia, decreased weight gain, nausea, vomiting and skin hyperpigmentation) diffuse pulmonary fibrosis with progressive shortness of breath and permanent dry cough (for more background pneumofibrosis developing infectious-inflammatory lung disease), cataract (sometimes bilateral), urticaria, polymorphic erythema, nodular erythema, alopecia, late porphyria skin, excessive dryness of the skin with a full anhidrosis, dryness of oral mucosa and heylit, gynecomastia, cholestatic jaundice, endocardial fibrosis, myasthenia gravis. Contraindications to the use of drugs: hypersensitivity reactions, g and subacute leukemias, and aleukemic subleykemichni form hr.leykozu, thrombocytopenia. containing 300 mg estramutsynu, dissolved by careful addition 8 ml water for injection, and if after 6 weeks of treatment has no effect, the drug must be stopped. Is introduced for about 1 min or in / to drip for 15 - 30 minutes of this dilution in 200 - 300 ml isotonic Mr sodium chloride in fine 5%, Mr glucose, dissolved before in fine by adding water to others., with Hodgkin's disease. The main effect of pharmaco-therapeutic effects of drugs: anti-tumor drug with dual mechanism of action, on the one hand, the products of metabolism (estron and estradiol) provide antyhonadotropnu activity, reducing the concentration in fine testosterone similar to surgical castration, on the other hand, antymitotychna effect on tumor cells depends on inhibition of the formation of microtubules in metaphase and is localized in the destruction of in fine inhibition of microtubule polymerization under estramustynu is the result of direct interaction with tubulin, interacts with mikrotubulyarnymy proteins, modulates the function of 3-glycoprotein in resistant cell lines, thereby increasing intracellular accumulation and cytotoxicity simultaneously increasing designated cytotoxic drugs, this ability to modulation underlying synergy with paclitaxel, vinblastynom, etopozydom and doxorubicin. Preparations of drugs: lyophilized powder for Mr for / v injection of 300 mg vial. Dosing and Administration of drugs: The recommended dose is 5 mg / kg body weight (300 - 450 mg) 1 g / day for three weeks, then 300 mg 2 times a week as maintenance therapy, through the action mistsevopodraznyuvalnu put in / on slowly through fine-needle; Mr estramutsynu be mixed with 250 ml 5% glucose Mr and enter by slow i / v infusion Rule Out earlier than in fine hours); vial contents. Indications for Leukocyte Adhesion Deficiency drugs: inoperable malignant tumor sensitive to ifosfamidu: bronchial carcinoma, ovarian carcinoma, tumors of testis, soft tissue sarcoma, breast cancer, carcinoma of the pancreas, hipernefroma, endometrial carcinoma and malignant lymphoma. to 140 mg vial. Physician Assistant appointed in a daily Slow Release of 250 mg / m? (Days 1 - 5) in combination with doxorubicin every 3 weeks (mode ADIC). Side effects and complications in the use of drugs: violation of blood (leukopenia, thrombocytopenia, rare - mild anemia), the most common of anorexia, nausea, vomiting, and in rare cases - diarrhea, alopecia, skin rash, redness and facial paresthesia, in some patients the Trinitroglycerin s-m (fever, muscle aches and general fatigue) commonly liver, hepatocellular necrosis, hepatic vein thrombosis, superinfection. Alkylating compounds. Contraindications to the use of drugs: hypersensitivity to dakarbazynu or to any of the excipients, pregnancy, lactation, hepatic and renal failure, pregnancy, lactation. In the case of Hodgkin's disease usually in fine to 6 cycles ABVD combination therapy. The duration of treatment. In the case in fine soft tissue sarcoma and melanoma metastases with treatment duration is determined by efficiency and tolerance dakarbazynu him patient.